Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 21, 2024; 30(19): 2603-2611
Published online May 21, 2024. doi: 10.3748/wjg.v30.i19.2603
Intestinal microecological transplantation for a patient with chronic radiation enteritis: A case report
Lin Wang, Yan Li, Yu-Jing Zhang, Li-Hua Peng
Lin Wang, Yan Li, Yu-Jing Zhang, Li-Hua Peng, Department of Gastroenterology and Hepatology, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China
Lin Wang, Yu-Jing Zhang, Department of Gastroenterology and Hepatology, Chinese PLA Medical School, Beijing 100853, China
Author contributions: Wang L was responsible for conceptualization and design of the study, data compilation and analysis, writing of the paper; Li Y, Zhang YJ were responsible for data compilation and analysis; Peng LH was responsible for conceptualization and design of the study, guiding the writing of the paper and quality control; all authors have read and agreed to the published version of the manuscript.
Informed consent statement: participant provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li-Hua Peng, MD, PhD, Department of Gastroenterology and Hepatology, The First Medical Center, Chinese PLA General Hospital, No. 28 FuXing Road, Beijing 100853, China. penglihua301@126.com
Received: January 23, 2024
Revised: April 18, 2024
Accepted: April 22, 2024
Published online: May 21, 2024
Core Tip

Core Tip: This study explores the efficacy of fecal microbiota transplantation (FMT) in a patient with chronic radiation enteritis. A 64-year-old patient experienced significant symptom relief and long-term remission after FMT. Microbial analysis revealed beneficial shifts in gut flora composition. This highlights FMT as a promising intervention for managing radiation-induced gastrointestinal complications, offering short-term relief and sustained benefits. Targeting intestinal microbiota presents a novel approach to improving patient outcomes and quality of life in chronic radiation enteritis, showing a potential paradigm shift in treatment strategies.