Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 21, 2024; 30(11): 1636-1643
Published online Mar 21, 2024. doi: 10.3748/wjg.v30.i11.1636
Myocardial metastasis from ZEB1- and TWIST-positive spindle cell carcinoma of the esophagus: A case report
Yoshihiro Shibata, Hirofumi Ohmura, Kazuki Komatsu, Kosuke Sagara, Atsuji Matsuyama, Ryuji Nakano, Eishi Baba
Yoshihiro Shibata, Kosuke Sagara, Department of Medical Oncology, Fukuoka Wajiro Hospital, Fukuoka 811-0213, Japan
Hirofumi Ohmura, Eishi Baba, Department of Oncology and Social Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka 812-8582, Japan
Kazuki Komatsu, Department of Pathology and Oncology, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan
Atsuji Matsuyama, Ryuji Nakano, Department of Diagnostic Pathology, Fukuoka Wajiro Hospital, Fukuoka 811-0213, Japan
Author contributions: Shibata Y, Ohmura H, and Baba E contributed to the design of the report and drafted the manuscript; Komatsu K, Sagara K, Matsuyama A, and Nakano R critically revised the manuscript.
Informed consent statement: Written, informed consent was obtained from the patient’s next of kin for publication of the details of the patient’s medical case and any accompanying images.
Conflict-of-interest statement: Hirofumi Ohmura has received speakers’ bureau from Ono Pharmaceutical; Eishi Baba has received honoraria from Ono Pharmaceutical and Bristol-Myers Squibb; All other authors have no conflicts of interest to report.
CARE Checklist (2016) statement: The authors have read CARE Checklist (2016), and the manuscript was prepared and revised according to CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Eishi Baba, MD, PhD, Professor, Department of Oncology and Social Medicine, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. baba.eishi.889@m.kyushu-u.ac.jp
Received: January 19, 2024
Peer-review started: January 19, 2024
First decision: January 31, 2024
Revised: February 2, 2024
Accepted: March 7, 2024
Article in press: March 7, 2024
Published online: March 21, 2024
Core Tip

Core Tip: Spindle cell carcinoma (SCC) is rare, accounting for about 0.1%-1.5% of esophageal cancers. Tumor cells show sarcomatoid differentiation with spindle cells and are accompanied by components of conventional carcinoma including squamous cell carcinoma in some cases. Many of cardiac metastatic tumors are asymptomatic and are typically discovered through pathological autopsy, with metastatic cardiac tumors being identified in 2% to 18% of cancer patients undergoing autopsy. There has been no report of cardiac metastasis in esophageal SCC.