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World J Gastroenterol. Jun 14, 2023; 29(22): 3400-3421
Published online Jun 14, 2023. doi: 10.3748/wjg.v29.i22.3400
Epidemiology of small intestinal bacterial overgrowth
Irina Efremova, Roman Maslennikov, Elena Poluektova, Ekaterina Vasilieva, Yury Zharikov, Andrey Suslov, Yana Letyagina, Evgenii Kozlov, Anna Levshina, Vladimir Ivashkin
Irina Efremova, Roman Maslennikov, Elena Poluektova, Ekaterina Vasilieva, Anna Levshina, Vladimir Ivashkin, Department of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, Moscow 119435, Russia
Roman Maslennikov, Elena Poluektova, Vladimir Ivashkin, The Scientific Community for Human Microbiome Research, Moscow 119435, Russia
Yury Zharikov, Andrey Suslov, Department of Human Anatomy and Histology, Sechenov University, Moscow 125009, Russia
Yana Letyagina, N.V. Sklifosovsky Institute of Clinical Medicine, Sechenov University, Moscow 119991, Russia
Evgenii Kozlov, Anna Levshina, Department of Clinical Immunology and Allergy, Sechenov University, Moscow 119991, Russia
Author contributions: Ivashkin V reviewed the idea; all authors contributed to the draft editing; Maslennikov R is the guarantor.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Roman Maslennikov, MD, PhD, Academic Editor, Assistant Professor, Doctor, Professor, Department of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, Pogodinskaya str., 1, bld. 1, Moscow 119435, Russia.
Received: March 16, 2023
Peer-review started: March 16, 2023
First decision: March 24, 2023
Revised: March 31, 2023
Accepted: May 11, 2023
Article in press: May 11, 2023
Published online: June 14, 2023
Core Tip

Core Tip: Small intestinal bacterial overgrowth (SIBO) is common in functional and organic bowel diseases, liver diseases, other diseases of digestive organs, a number of endocrine, nervous, and rheumatic diseases, asthma, heart failure, and certain other diseases. In a number of diseases, including cirrhosis, metabolic-associated fatty liver disease, diabetes mellitus, pancreatitis, and cystic fibrosis, an association was found between disease severity and the presence of SIBO. Further work on the effect of SIBO eradication on the condition and prognosis of patients in various diseases is required.