High incidence combination of multiple primary malignant tumors of the digestive system
Xiao-Bo Yang, Long-Hao Zhang, Jing-Nan Xue, Yun-Chao Wang, Xu Yang, Nan Zhang, Dan Liu, Yan-Yu Wang, Zi-Yu Xun, Yi-Ran Li, Hui-Shan Sun, Li-Jin Zhao, Hai-Tao Zhao
Xiao-Bo Yang, Long-Hao Zhang, Jing-Nan Xue, Yun-Chao Wang, Xu Yang, Nan Zhang, Yan-Yu Wang, Zi-Yu Xun, Yi-Ran Li, Hui-Shan Sun, Hai-Tao Zhao, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100006, China
Long-Hao Zhang, Jing-Nan Xue, Dan Liu, Li-Jin Zhao, Digestive Disease Hospital Affiliated to Zunyi Medical University, Department of General Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi 563099, Guizhou Province, China
Author contributions: Yang XB, Zhang LH, Xue JN contributed equally to this work; Wang YC, Yang X, Liu D, Wang YY and Xun ZY performed the radiological diagnosis; Zhang LH, Xue JN performed pathological diagnosis; Yang XB, Zhang LH designed the research study; Xue JN, Zhang N, Li YR and Sun HS performed the primary literature and data extraction; Yang XB and Zhang LH analysed the data and wrote the manuscript; Zhao HT and Zhao LJ were responsible for revising the manuscript for important knowledge content and contributed equally to this work, and all authors read and approved the final version.
Supported by the CAMS Innovation Fund for Medical Sciences, No. 2021-I2M-1-061 and 2021-1-I2M-003; CSCO-hengrui Cancer Research Fund, No. Y-HR2019-0239; CSCO-MSD Cancer Research Fund, No. Y-MSDZD2021-0213; and National Ten-thousand Talent Program.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Peking Union Medical College (Approval No. K22C0171).
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data. The ethical Committee of Peking Union Medical College Hospital agreed to waive the informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Hai-Tao Zhao, PhD, Professor, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 1 Shuaifuyuan, Dongcheng District, Beijing 100006, China. zhaoht@pumch.cn
Received: August 24, 2022
Peer-review started: August 24, 2022
First decision: September 26, 2022
Revised: September 29, 2022
Accepted: October 26, 2022
Article in press: October 26, 2022
Published online: November 7, 2022
