Alberca GGF, Cardoso NSS, Solis-Castro RL, Nakano V, Alberca RW. Intestinal inflammation and the microbiota: Beyond diversity. World J Gastroenterol 2022; 28(26): 3274-3278 [PMID: 36051343 DOI: 10.3748/wjg.v28.i26.3274]
Corresponding Author of This Article
Ricardo Wesley Alberca, PhD, Academic Research, Research Fellow, Laboratorio de Dermatologia e Imunodeficiencias, Departamento de Dermatologia, Faculdade de Medicina FMUSP, Universidade de São Paulo, 455-Cerqueira César, São Paulo 01246-903, Brazil. ricardowesley@gmail.com
Research Domain of This Article
Immunology
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Gabriela Gama Freire Alberca, Naiane Samira Souza Cardoso, Viviane Nakano, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil
Rosa Liliana Solis-Castro, Departamento Académico de Biología Bioquímica, Facultad de Ciencias de la Salud, Universidad Nacional de Tumbes, Pampa Grande 24000, Tumbes, Peru
Ricardo Wesley Alberca, Laboratorio de Dermatologia e Imunodeficiencias, Departamento de Dermatologia, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo 01246-903, Brazil
Author contributions: All authors wrote and reviewed the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ricardo Wesley Alberca, PhD, Academic Research, Research Fellow, Laboratorio de Dermatologia e Imunodeficiencias, Departamento de Dermatologia, Faculdade de Medicina FMUSP, Universidade de São Paulo, 455-Cerqueira César, São Paulo 01246-903, Brazil. ricardowesley@gmail.com
Received: August 6, 2021 Peer-review started: August 6, 2021 First decision: September 4, 2021 Revised: September 5, 2021 Accepted: June 23, 2022 Article in press: June 23, 2022 Published online: July 14, 2022
Core Tip
Core Tip: The manuscript entitled “Relationship between clinical features and intestinal microbiota in Chinese patients with ulcerative colitis” and previous investigations have identified alterations in the intestinal microbiome of patients with inflammatory bowel disease, ulcerative colitis, and colorectal cancer. The microbiota composition impacts the development of inflammatory disorders. Nevertheless, investigations should focus on identifying alterations not only on the diversity of the microbiota but the presence of the toxin-producing bacteria. Further investigations should investigate alterations in the microbiota composition and the production of toxins by commensal bacteria such as Escherichia coli, Clostridium perfringens, and Bacteroides fragilis.
