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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 28, 2021; 27(8): 725-736
Published online Feb 28, 2021. doi: 10.3748/wjg.v27.i8.725
Published online Feb 28, 2021. doi: 10.3748/wjg.v27.i8.725
Endoscopic full-thickness resection using an over-the-scope device: A prospective study
Jin-Tao Guo, Jing-Jing Zhang, Yu-Fan Wu, Ye Liao, Yi-Dan Wang, Bao-Zhen Zhang, Sheng Wang, Si-Yu Sun, Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China
Author contributions: Guo JT and Zhang JJ were involved in the study conception and design; Guo JT, Wang S, and Sun SY performed the research; Liao Y, Wu YF, Zhang BZ, and Wang YD analyzed the data; Guo JT wrote the manuscript; Guo JT and Sun SY performed critical revision of the article for important intellectual content; all authors approved the final version of the article.
Supported by National Natural Science Foundation of China , No. 81900601 ; Innovative Talent Support Program of Liaoning Province , No. LR2019073 ; and Outstanding Scientific Fund of Shengjing Hospital , No. 201701 and No. 201702 .
Institutional review board statement: This study was reviewed and approved by the Internal Review Board and Ethics Committee of China Medical University.
Clinical trial registration statement: The clinical trial is registered with Chinese Clinical Trial Registry, using identifier ChiCTR-OPC-14005459.
Informed consent statement: All study participants, or their legal guardian, provided written consent prior to study enrollment.
Conflict-of-interest statement: The authors of this manuscript having no conflicts of interest to disclose.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Si-Yu Sun, MD, PhD, Chief Doctor, Director, Professor, Department of Gastroenterology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Shenyang 110004, Liaoning Province, China. sun-siyu@163.com
Received: November 10, 2020
Peer-review started: November 10, 2020
First decision: December 3, 2020
Revised: December 13, 2020
Accepted: January 21, 2021
Article in press: January 21, 2021
Published online: February 28, 2021
Peer-review started: November 10, 2020
First decision: December 3, 2020
Revised: December 13, 2020
Accepted: January 21, 2021
Article in press: January 21, 2021
Published online: February 28, 2021
Core Tip
Core Tip: A prospective study of endoscopic full-thickness resection (EFTR) combined with an over-the-scope clip (OTSC) was conducted to assess the treatment of mucosal and submucosal lesions that are not amenable to conventional endoscopic resection techniques. The study had a long follow-up period and included a large number of cases, thus providing statistical strength. We found that EFTR combined with an OTSC was a safe and effective treatment modality for mucosal and submucosal lesions that cannot be treated using conventional endoscopic resection techniques.