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Shahini E, Maida M. Surveillance strategies for precancerous gastric conditions after Helicobacter pylori eradication: There is still need for a tailored approach. World J Gastroenterol 2021; 27(46): 8033-8039 [PMID: 35046629 DOI: 10.3748/wjg.v27.i46.8033]
Author contributions: Shahini E conducted study conceptualization, drafting the manuscript, data collecting, and curation; Maida M supervised; Shahini E and Maida M edited paper, critically reviewed the data entries for important intellectual content, checked for completeness of information; and both authors approved the final draft.
Conflict-of-interest statement: All the authors have no conflict of interest related to the manuscript.
Corresponding author: Endrit Shahini, MD, MSc, Division of Gastroenterology, National Institute of Research "Saverio De Bellis", Via Turi, 27, Castellana Grotte (Bari) 70013, Italy.endrit.shahini@irccsdebellis.it
Received: September 4, 2021 Peer-review started: September 4, 2021 First decision: October 2, 2021 Revised: October 3, 2021 Accepted: November 25, 2021 Article in press: November 25, 2021 Published online: December 14, 2021 Processing time: 96 Days and 15.8 Hours
Core Tip
Core Tip: Prevailing evidence affirms that Helicobacter pylori (H. pylori) eradication therapy could shift precancerous gastric conditions and positively confines gastric cancer risk during long-term endoscopic follow-up. Nonetheless, there is a yet unsolved dispute concerning the most useful individualized surveillance strategies following H. pylori eradication, based on malignant risk stratification. These aspects should be examined in the next future to establish and optimize the most cost-effective strategies for recognizing and managing H. pylori-positive patients with precancerous gastric conditions in the short- and long-term follow-up. Accordingly, new studies are required to sharpen the hazard stratification of patients with the greatest chance of progressing into gastric cancer.