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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 14, 2021; 27(38): 6415-6429
Published online Oct 14, 2021. doi: 10.3748/wjg.v27.i38.6415
Published online Oct 14, 2021. doi: 10.3748/wjg.v27.i38.6415
Faecal immunochemical test outside colorectal cancer screening?
Noel Pin-Vieito, Manuel Puga, Daniel Fernández-de-Castro, Joaquín Cubiella, Department of Gastroenterology, Complexo Hospitalario Universitario de Ourense, Instituto de Investigación Sanitaria Galicia Sur, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Ourense 32005, Spain
Author contributions: All authors contributed equally to the manuscript in the conception and design of the article, acquisition of data, analysis and interpretation of data; drafting the article or making critical revisions related to important intellectual content of the manuscript, and final approval of the version of the article to be published.
Supported by Spain’s Carlos III Health Care Institute by Means of Project (Co-funded by European Regional Development Fund/European Social Fund "A way to make Europe"/"Investing in your future") , No. PI17/00837 .
Conflict-of-interest statement: No conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Joaquín Cubiella, MD, PhD, Doctor, Staff Physician, Statistician, Department of Gastroenterology, Complexo Hospitalario Universitario de Ourense, Instituto de Investigación Sanitaria Galicia Sur, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Rúa Ramón Puga 52-56, Ourense 32005, Spain. joaquin.cubiella.fernandez@sergas.es
Received: April 7, 2021
Peer-review started: April 7, 2021
First decision: June 26, 2021
Revised: June 27, 2021
Accepted: August 16, 2021
Article in press: August 16, 2021
Published online: October 14, 2021
Peer-review started: April 7, 2021
First decision: June 26, 2021
Revised: June 27, 2021
Accepted: August 16, 2021
Article in press: August 16, 2021
Published online: October 14, 2021
Core Tip
Core Tip: Faecal immunochemical test (FIT) is a colorectal cancer (CRC) diagnostic biomarker used widely in CRC screening programmes. In recent years, a large body of evidence has appeared that enables recommending its use in different scenarios. For the evaluation of symptomatic patients in primary healthcare, FIT improves use of available endoscopic resources, avoiding unnecessary colonoscopies, predicts the risk of CRC and may have an impact on prognosis. Furthermore, although endoscopic surveillance after adenoma resection is widely extended, there are relevant doubts over its efficiency in the context of high-quality baseline colonoscopies and a FIT-based surveillance strategy could be an alternative.