Observational Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 7, 2021; 27(37): 6290-6305
Published online Oct 7, 2021. doi: 10.3748/wjg.v27.i37.6290
Helicobacter pylori in gastric cancer: Features of infection and their correlations with long-term results of treatment
Marina A Senchukova, Olesya Tomchuk, Elena I Shurygina
Marina A Senchukova, Department of Oncology, Orenburg State Medical University, Orenburg 460000, Russia
Olesya Tomchuk, Department of Histology, Cytology, Embryology, Orenburg State Medical University, Orenburg 460000, Russia
Elena I Shurygina, Department of Pathology, Orenburg State Medical University, Orenburg 460000, Russia
Author contributions: Senchukova MA wrote the paper; Tomchuk O and Shurygina EI perfomed the collected the data.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of the Orenburg State Medical University.
Informed consent statement: All patients provided written informed consent.
Conflict-of-interest statement: The authors declare no conflicts of interests related to the publication of this study.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Marina A Senchukova, MD, PhD, Professor, Department of Oncology, Orenburg State Medical University, Sovetskaya Street 6, Orenburg 460000, Russia. masenchukova@yandex.com
Received: April 30, 2021
Peer-review started: April 30, 2021
First decision: June 17, 2021
Revised: June 21, 2021
Accepted: August 31, 2021
Article in press: August 31, 2021
Published online: October 7, 2021
Core Tip

Core Tip: The role of Helicobacter pylori (H. pylori) in the progression of gastric cancer (GC) is not well understood. Our results indicate that in GC, a high degree of gastric mucosa contamination by coccoid forms of H. pylori is associated with advanced stages of the disease and deterioration of long-term results of treatment.