Diagnosis of focal liver lesions with deep learning-based multi-channel analysis of hepatocyte-specific contrast-enhanced magnetic resonance imaging
Róbert Stollmayer, Bettina K Budai, Ambrus Tóth, Ildikó Kalina, Viktor Bérczi, Pál Maurovich-Horvat, Pál N Kaposi, Department of Radiology, Medical Imaging Centre, Faculty of Medicine, Semmelweis University, Budapest 1083, Hungary
Erika Hartmann, Department of Transplantation and Surgery, Faculty of Medicine, Semmelweis University, Budapest 1082, Hungary
Péter Szoldán, MedInnoScan Research and Development Ltd., Budapest 1112, Hungary
Author contributions: Stollmayer R designed and performed the research and wrote the paper; Budai BK and Tóth A contributed to data collection and analysis; Kalina I and Hartmann E provided clinical advice; Szoldán P contributed to the analysis; Bérczi V and Maurovich-Horvat P supervised the report; Kaposi PN designed the research, contributed to the analysis and supervised the report; all authors have read and approved the final manuscript.
Institutional review board statement: The present study has been approved by the institutional ethics committee of Semmelweis University (Semmelweis University Regional and Institutional Committee of Science and Research Ethics) according to the World Medical Association guidelines and Declaration of Helsinki, revised in 2000 in Edinburgh, No. SE-RKEB 136/2019.
Informed consent statement: As this is a retrospective study, in compliance with the Hungarian legal code, the need for written patient consent was waived by the ethics committee. Patients were not required to give informed consent to the study because the analysis used only anonymized clinical data that were obtained after each patient agreed to treatment and gave written informed consent to the MRI scan in compliance with our institutional protocol.
Conflict-of-interest statement: The authors have no financial relationships to disclose.
Data sharing statement: Additional anonymized data are available upon request from the corresponding author.
: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bettina K Budai, MD, Department of Radiology, Medical Imaging Centre, Faculty of Medicine, Semmelweis University, Korányi Sándor st. 2., Budapest 1083, Hungary. email@example.com
Received: April 30, 2021
Peer-review started: April 30, 2021
First decision: June 23, 2021
Revised: July 7, 2021
Accepted: August 25, 2021
Article in press: August 25, 2021
Published online: September 21, 2021