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World J Gastroenterol. Jul 14, 2021; 27(26): 4172-4181
Published online Jul 14, 2021. doi: 10.3748/wjg.v27.i26.4172
Adult pancreatoblastoma: Current concepts in pathology
Ayo O Omiyale
Ayo O Omiyale, Department of Cellular Pathology, Imperial College Healthcare NHS Trust, London W6 8RF, United Kingdom
Author contributions: Omiyale AO reviewed the literature and wrote the manuscript.
Conflict-of-interest statement: The author declares no conflict of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ayo O Omiyale, MBChB, MPH, Doctor, Department of Cellular Pathology, Imperial College Healthcare NHS Trust, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, United Kingdom. ayodeji.omiyale@nhs.net
Received: January 30, 2021
Peer-review started: January 30, 2021.
First decision: March 6, 2021
Revised: March 23, 2021
Accepted: June 22, 2021
Article in press: June 22, 2021
Published online: July 14, 2021
Core Tip

Core Tip: Adult pancreatoblastomas are extremely rare tumours of the pancreas. They are composed of neoplastic cells with multiple lines of differentiation and characteristic squamoid nests. They mimic other neoplasms of the pancreas, which may give rise to diagnostic difficulties. This article provides an up-to-date review of the clinical and pathologic features of pancreatoblastoma in adults, including differential diagnosis, treatment, and follow-up.