Copyright
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 28, 2021; 27(20): 2576-2585
Published online May 28, 2021. doi: 10.3748/wjg.v27.i20.2576
Published online May 28, 2021. doi: 10.3748/wjg.v27.i20.2576
COVID-19 in normal, diseased and transplanted liver
Alessandro Signorello, Ilaria Lenci, Martina Milana, Giuseppe Grassi, Leonardo Baiocchi, Hepatology Unit, Department of Medicine, University of Tor Vergata, Rome 00133, Italy
Author contributions: Signorello A performed acquisition of data, analysis and interpretation, drafting of manuscript, critical revision; Lenci I, Milana M, and Grassi G performed acquisition of data, critical revision; Baiocchi L performed proposal of study, study conception, correction of manuscript, critical revision.
Conflict-of-interest statement: No conflict of interest to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Leonardo Baiocchi, MD, PhD, Associate Professor, Hepatology Unit, Department of Medicine, University of Tor Vergata, Viale Oxford 81, Rome 00133, Italy. baiocchi@uniroma2.it
Received: February 18, 2021
Peer-review started: February 18, 2021
First decision: March 12, 2021
Revised: March 18, 2021
Accepted: May 7, 2021
Article in press: May 7, 2021
Published online: May 28, 2021
Peer-review started: February 18, 2021
First decision: March 12, 2021
Revised: March 18, 2021
Accepted: May 7, 2021
Article in press: May 7, 2021
Published online: May 28, 2021
Core Tip
Core Tip: Severe acute respiratory syndrome coronavirus 2 infection, starting from December 2019 in China, has now extended in the whole world. While the respiratory system is mainly involved in the infection other organs may be impaired by coronavirus disease 2019 (COVID-19). In this review we report the current finding regarding the liver during this infection. While mild liver effects occur in normal subjects with COVID-19, severe sequelae may be expected in individuals with a reduced hepatic reserve.