Effect of probiotics on length of hospitalization in mild acute pancreatitis: A randomized, double-blind, placebo-controlled trial
You-Dong Wan, Tong-Wen Sun, Integrated Intensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China
Rui-Xue Zhu, Health Management Centre, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Zhong-Zheng Bian, Department of Emergency Medicine, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Author contributions: Wan YD wrote the paper; Wan YD and Zhu RX collected and analyzed the data; Wan YD, Zhu RX, Bian ZZ, and Sun TW designed the study, critically reviewed the manuscript, and approved the final version.
Supported by National Natural Science Foundation of China, No. 81370364.
Institutional review board statement: The study was ethically approved by the Ethics Committee of The Affiliated Hospital of Qingdao University.
Clinical trial registration statement: The trial was registered in the Chinese Clinical Trial Registry (ChiCTR2000030425).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflict of interests for this article.
CONSORT 2010 statement: The authors have read the CONSORT Statement—checklist of items, and the manuscript was prepared and revised according to the CONSORT Statement—checklist of items.
: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tong-Wen Sun, MD, Chief Doctor, Professor, Integrated Intensive Care Unit, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou 450052, Henan Province, China. firstname.lastname@example.org
Received: November 5, 2020
Peer-review started: November 5, 2020
First decision: November 25, 2020
Revised: November 29, 2020
Accepted: December 16, 2020
Article in press: December 16, 2020
Published online: January 14, 2021