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World J Gastroenterol. Apr 28, 2021; 27(16): 1751-1769
Published online Apr 28, 2021. doi: 10.3748/wjg.v27.i16.1751
Preoperative physiological esophageal assessment for anti-reflux surgery: A guide for surgeons on high-resolution manometry and pH testing
Michael Yodice, Alexandra Mignucci, Virali Shah, Christopher Ashley, Micheal Tadros
Michael Yodice, Alexandra Mignucci, Virali Shah, Department of Gastroenterology, Albany Medical College, Albany, NY 12208, United States
Christopher Ashley, Section of Gastroenterology, Stratton VA Medical Center, Albany, NY 12208, United States
Micheal Tadros, Department of Gastroenterology, Albany Medical Center, Schenectady, NY 12309, United States
Author contributions: Yodice M contributed as lead author with manuscript preparation. Mignucci A and Shah V contributed equally with manuscript preparation and critical review; Ashley C contributed critical review for the manuscript; Tadros M is the guarantor of the manuscript and also provided critical review.
Conflict-of-interest statement: The authors disclose no conflicts of interest or external funding for this publication.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Micheal Tadros, FACG, MD, Associate Professor, Doctor, Department of Gastroenterology, Albany Medical Center, 1769 Union Street 2nd Floor, Schenectady, NY 12309, United States. tadrosm1@amc.edu
Received: January 23, 2021
Peer-review started: January 23, 2021
First decision: February 10, 2021
Revised: February 18, 2021
Accepted: March 25, 2021
Article in press: March 25, 2021
Published online: April 28, 2021
Core Tip

Core Tip: The goal of this review is to discuss recent technological advancements that have utility for patients with gastroesophageal reflux disease (GERD) as a pre-operative assessment for anti-reflux surgery. Surgical treatment of GERD is centered around improving the integrity of the lower esophageal sphincter, therefore it is crucial to rule out other esophageal pathologies that may present with GERD-like symptoms. Advances in pH-impedance studies allow for assessment of patients with weak acid reflux of non-erosive reflux disease. High resolution manometry with the addition of provocative measures can uncover underlying esophageal motility disorders with GERD-like symptoms.