Apolipoprotein E variants correlate with the clinical presentation of paediatric inflammatory bowel disease: A cross-sectional study
Aleksandra Glapa-Nowak, Mariusz Szczepanik, Jarosław Walkowiak, Department of Pediatric Gastroenterology and Metabolic Diseases, Poznań University of Medical Sciences, Poznań 60-572, Poland
Barbara Iwańczak, Department of Pediatrics, Medical University of Wroclaw, Wroclaw 50-369, Poland
Jarosław Kwiecień, Department of Pediatrics, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Zabrze 41-800, Poland
Urszula Grzybowska-Chlebowczyk, Department of Pediatrics, Faculty of Medical Sciences, Medical University of Silesia in Katowice, Katowice 40-752, Poland
Marcin Osiecki, Jarosław Kierkuś, Department of Gastroenterology, Hepatology, Feeding Disorders and Paediatrics, The Children’s Memorial Health Institute, Warsaw 04-730, Poland
Marcin Dziekiewicz, Aleksandra Banaszkiewicz, Department of Pediatric Gastroenterology and Nutrition, Medical University of Warsaw, Warsaw 02-091, Poland
Andrzej Stawarski, Department and Clinic of Pediatrics, Gastroenterology and Nutrition, Wroclaw Medical University, Wroclaw 50-369, Poland
Tomasz Banasiewicz, Chair and Department of General Surgery, Gastroenterological Surgical Oncology and Plastic Surgery, Poznań University of Medical Sciences, Poznań 60-355, Poland
Author contributions: Glapa-Nowak A, Szczepanik M, and Walkowiak J contributed to conceptualization and administration; Glapa-Nowak A and Walkowiak J contributed to formal analysis and funding acquisition; Szczepanik M, and Walkowiak J designed and coordinated the study; Glapa-Nowak A, Szczepanik M, Iwańczak B, Kwiecien J, Szaflarska-Popławska AB, Grzybowska-Chlebowczyk U, Osiecki M, Dziekiewicz M, Stawarski A, Kierkuś J, Banasiewicz T, and Banaszkiewicz A wrote the manuscript and acquired and analysed data; All authors approved the final version of the article.
Supported by The National Science Centre, Poland, No. 2017/25/B/NZ5/02783 (to Walkowiak J).
Institutional review board statement: The study obtained the approval of the Bioethical Committee at Poznań University of Medical Sciences (960/15 with the associated amendments).
Informed consent statement: Patients gave informed consent to the study. The analysis used anonymous clinical data after each patient agreed to participate by written consent.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jarosław Walkowiak, MD, PhD, Professor, Department of Pediatric Gastroenterology and Metabolic Diseases, Poznań University of Medical Sciences, Szpitalna Street 27/33, Poznań 60-572, Poland. firstname.lastname@example.org
Received: September 18, 2020
Peer-review started: September 18, 2020
First decision: November 3, 2020
Revised: November 17, 2020
Accepted: February 25, 2021
Article in press: February 25, 2021
Published online: April 14, 2021