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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 28, 2020; 26(8): 839-849
Published online Feb 28, 2020. doi: 10.3748/wjg.v26.i8.839
Published online Feb 28, 2020. doi: 10.3748/wjg.v26.i8.839
Prognostic value of preoperative weight loss-adjusted body mass index on survival after esophagectomy for esophageal squamous cell carcinoma
Han-Lu Zhang, Yu-Shang Yang, Qi-Xin Shang, Yi-Min Gu, Wei-Peng Hu, Wen-Ping Wang, Yang Hu, Yun Wang, Yong Yuan, Long-Qi Chen, Department of Thoracic Surgery, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Jia-Nan Duan, Department of Ophthalmology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Song-Lin He, Department of Thoracic and Cardiovascular Surgery, the Second People's Hospital of Chengdu, Chengdu 610017, Sichuan Province, China
Author contributions: Zhang HL and Yang YS wrote the manuscript and made the data analysis; Zhang HL, Yuan Y, Chen LQ and Wang Y revised the manuscript; Duan JN, Shang QX, He SL and Gu YM made the data collection and performed the follow-up; Wang WP and Hu Y provided clinical advice; Yuan Y, Chen LQ and Wang Y made the conception and design of the study.
Supported by National Natural Science Foundation of China , No. 81970481 ; Sichuan Science and Technology Program , No. 2018HH0150 ; Chengdu Science and Technology Bureau ; No. 2017GH00072 .
Institutional review board statement: The study protocol was approved by West China Hospital of Sichuan University Biomedical Research Ethics Committee.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All authors declare no conflicts-of-interest related to this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Yong Yuan, MD, PhD, Associate Professor, Department of Thoracic Surgery, West China Hospital of Sichuan University, No. 37 Guoxue Alley, Chengdu 610041, Sichuan Province, China. dy818@sina.com
Received: October 9, 2019
Peer-review started: October 9, 2019
First decision: December 23, 2019
Revised: January 13, 2020
Accepted: January 24, 2020
Article in press: January 24, 2020
Published online: February 28, 2020
Peer-review started: October 9, 2019
First decision: December 23, 2019
Revised: January 13, 2020
Accepted: January 24, 2020
Article in press: January 24, 2020
Published online: February 28, 2020
Core Tip
Core tip: The aim of this study was to explore the impact of preoperative weight loss (PWL)-adjusted body mass index (BMI) on overall survival for patients undergoing surgery for esophageal squamous cell carcinoma. Patients with BMI ≥ 20.0 kg/m2 and PWL < 8.8% were classified into Group 1. Patients with BMI < 20.0 kg/m2 and PWL < 8.8% were classified into Group 2. Patients with PWL ≥ 8.8% were classified into Group 3. Patients in the three groups were associated with significantly different overall survival. This result indicates that PWL-adjusted BMI has prognostic value for patients undergoing surgery for esophageal squamous cell carcinoma.