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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 21, 2020; 26(35): 5343-5353
Published online Sep 21, 2020. doi: 10.3748/wjg.v26.i35.5343
Published online Sep 21, 2020. doi: 10.3748/wjg.v26.i35.5343
Updated bone mineral density status in Saudi patients with inflammatory bowel disease
Mohammed Ewid, Internal Medicine Department, College of Medicine, Sulaiman Al Rajhi University, Bukairyah 51941, Al-Qassim, Saudi Arabia
Mohammed Ewid, Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo 11562, Egypt
Nawaf Al Mutiri, Khalid Al Omar, Amal N Shamsan, Awais A Rathore, Gastroenterology Department, King Fahad Specialist Hospital, Buraidah 52366, Al-Qassim, Saudi Arabia
Nazmus Saquib, Epidemiology Department, College of Medicine, Sulaiman Al Rajhi University, Bukairyah 51941, Al-Qassim, Saudi Arabia
Anas Salaas, Omar Al Sarraj, Yaman Nasri, Ahmed Attal, Abdulrahman Tawfiq, Medical students, College of Medicine, Sulaiman Al Rajhi University, Bukairyah 51941, Al-Qassim, Saudi Arabia
Hossam Sherif, Critical Care Medicine Department, College of Medicine, Sulaiman Al Rajhi University, Bukairyah 51941, Al-Qassim, Saudi Arabia
Hossam Sherif, Critical Care Medicine Department, Faculty of Medicine, Cairo University, Cairo 11562, Egypt
Author contributions: Ewid M, Al Mutiri N, Saquib N, and Sherif H conceived of the idea, developed the theory; Ewid M was the principle investigator; all author contributed towards methodology and towards the writing of the paper, and have read and approved the final manuscript.
Supported by Sulaiman Al Rajhi University, Saudi Arabia, from the Annual Budget of their Research Unit .
Institutional review board statement: The study received ethical approval from the Regional Research Ethics Committee-Qassim province, Ministry of Health, Saudi Arabia (approval number 20180102).
Informed consent statement: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Data sharing statement: The datasets used and/or analyzed during the current study are available from the corresponding author upon reasonable request.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Mohammed Ewid, MD, Assistant Professor, Internal Medicine Department, College of Medicine, Sulaiman Al Rajhi University, PO Box 777, Bukairyah 51941, Al-Qassim, Saudi Arabia. drmohammedowid@yahoo.com
Received: May 8, 2020
Peer-review started: May 8, 2020
First decision: June 8, 2020
Revised: June 15, 2020
Accepted: August 22, 2020
Article in press: August 22, 2020
Published online: September 21, 2020
Peer-review started: May 8, 2020
First decision: June 8, 2020
Revised: June 15, 2020
Accepted: August 22, 2020
Article in press: August 22, 2020
Published online: September 21, 2020
Core Tip
Core Tip: Saudi patients with inflammatory bowel disease still have a high prevalence of reduced bone mineral density. Osteopenia and osteoporosis burdens were 19% and 37% in Crohn’s disease (CD) patients, and 7% and 25% in ulcerative colitis patients, respectively. Low body mass index is a significant risk factor for reduced bone mineral density in CD patients.