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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 7, 2020; 26(33): 5008-5021
Published online Sep 7, 2020. doi: 10.3748/wjg.v26.i33.5008
Published online Sep 7, 2020. doi: 10.3748/wjg.v26.i33.5008
Radiomics of rectal cancer for predicting distant metastasis and overall survival
Mou Li, Yu-Feng Yue, Hao-Peng Yu, Bin Song, Department of Radiology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Yu-Zhou Zhu, Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Yong-Chang Zhang, Department of Radiology, Chengdu Seventh People’s Hospital, Chengdu 610213, Sichuan Province, China
Author contributions: All authors helped to perform the research; Song B and Zhu YZ designed the research; Li M and Zhang YC performed the research; Li M, Yue YF, Song B, and Yu HP analyzed the data; Li M and Song B wrote the paper.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of West China Hospital of Sichuan University.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All authors declare no conflicts of interest related to this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Bin Song, MD, PhD, Chief Doctor, Professor, Department of Radiology, West China Hospital of Sichuan University, No. 37, Guoxue Alley, Chengdu 610041, Sichuan Province, China. songlab_radiology@163.com
Received: May 27, 2020
Peer-review started: May 27, 2020
First decision: June 4, 2020
Revised: June 16, 2020
Accepted: August 13, 2020
Article in press: August 13, 2020
Published online: September 7, 2020
Peer-review started: May 27, 2020
First decision: June 4, 2020
Revised: June 16, 2020
Accepted: August 13, 2020
Article in press: August 13, 2020
Published online: September 7, 2020
Core Tip
Core tip: We developed and validated a combined model that incorporated radiomic features and clinical factors. This model showed excellent potential for predicting distant metastasis of rectal cancer (RC) within 3 years after surgery. We used this model to stratify the patients with RC into low-risk and high-risk groups for the survival analysis. Overall survival rates between the low-risk and high-risk groups were significantly different. This model may aid in individualized prediction of distant metastasis and 3-year overall survival in patients with RC.