High plasma levels of COL10A1 are associated with advanced tumor stage in gastric cancer patients
Laura Necula, Lilia Matei, Denisa Dragu, Ioana Pitica, Ana Iulia Neagu, Coralia Bleotu, Carmen C Diaconu, Mihaela Chivu-Economescu, Department of Cellular and Molecular Pathology, Stefan S. Nicolau Institute of Virology, Bucharest 030304, Romania
Laura Necula, Titu Maiorescu University, Faculty of Medicine, Bucharest 040441, Romania
Simona Dima, Irinel Popescu, Fundeni Clinical Institute, Bucharest 022328, Romania
Author contributions: Necula L and Matei L equally contributed to this paper. Necula L, Chivu-Economescu M, and Matei L designed research; Dima S and Popescu I treated patients and collected material and clinical data from patients; Necula L, Matei L, Dragu D, and Pitica I performed the assays; Necula L, Matei L, Bleotu C, Diaconu CC, Chivu-and Economescu M analysed data; Necula L, Matei L, Neagu AI, and Chivu-Economescu M wrote the paper.
Supported by the Romanian National Authority for Scientific Research and Innovation, CNCS - UEFISCDI, No. PN-III-P4-ID-PCCF-2016-0158 (contract PCCF 17/2018), within PNCDI III.
Institutional review board statement: The study was reviewed and approved by the Stefan S. Nicolau Institute of Virology.
Conflict-of-interest statement: This work was supported by a grant of the Romanian Authority for Scientific Research and Innovation, CNCS - UEFISCDI, No. PN-III-P4-ID-PCCF-2016-0158 (contract PCCF 17/2018), within PNCDI III. All other authors have nothing to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Mihaela Chivu-Economescu, PhD, Research Assistant Professor, Research Scientist, Senior Researcher, Department of Cellular and Molecular Pathology, Stefan S. Nicolau Institute of Virology, 285 Mihai Bravu Ave, Bucharest 030304, Romania. firstname.lastname@example.org
Received: December 24, 2019
Peer-review started: December 28, 2019
First decision: January 19, 2020
Revised: May 14, 2020
Accepted: May 28, 2020
Article in press: May 28, 2020
Published online: June 14, 2020