Case Control Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 28, 2020; 26(20): 2632-2644
Published online May 28, 2020. doi: 10.3748/wjg.v26.i20.2632
Anhedonia and functional dyspepsia in obese patients: Relationship with binge eating behaviour
Antonella Santonicola, Mario Gagliardi, Giovanni Asparago, Luna Carpinelli, Luigi Angrisani, Paola Iovino
Antonella Santonicola, Mario Gagliardi, Giovanni Asparago, Luna Carpinelli, Paola Iovino, Gastroenterology Unit, Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Baronissi 84081, Salerno, Italy
Luigi Angrisani, General and Endoscopic Surgery Unit, San Giovanni Bosco Hospital, Naples 80100, Italy
Author contributions: Santonicola A and Iovino P designed research; Asparago G, Carpinelli L, Angrisani L collected the data and revised the paper. Santonicola A and Iovino P analyzed data; Santonicola A, Iovino P and Gagliardi M wrote the paper.
Institutional review board statement: The study received Ethics Committee approval and was conducted in accordance with the principles of the Declaration of Helsinki and good clinical practice.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors have no proprietary, financial, professional or other personal interest of any nature or kind in any product, service and/or company that could be construed as influencing the position presented in, or the review of this manuscript.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Paola Iovino, MD, Associate Professor, Department of Medicine, Surgery and Dentistry Scuola Medica Salernitana, University of Salerno, S Allende, Baronissi 84081, Salerno, Italy.
Received: December 31, 2019
Peer-review started: December 31, 2019
First decision: April 25, 2020
Revised: May 9, 2020
Accepted: May 16, 2020
Article in press: May 16, 2020
Published online: May 28, 2020
Core Tip

Core tip: Binge eating disorders (BED) co-occur with mood disorders and anxiety, whereas the relationship with anhedonia in obese patients undergoing sleeve gastrectomy (SG) is not known. We studied two group of morbidly obese patients with and without SG to assess the relationships among anhedonia, BED and functional dyspepsia. Our results suggest that a more regular screening for functional dyspepsia in SG candidates might help to disclose the presence of BED that may jeopardize postsurgical outcomes. Although anhedonia was not associated with BED in this study, worse surgical outcome was observed in patients with anhedonia independent of early satiety and postprandial fullness.