Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 21, 2020; 26(19): 2323-2332
Published online May 21, 2020. doi: 10.3748/wjg.v26.i19.2323
Gastrointestinal and hepatic manifestations of COVID-19: A comprehensive review
Ming Han Cha, Miguel Regueiro, Dalbir S Sandhu
Ming Han Cha, Department of Internal Medicine, Cleveland Clinic, Akron General, Akron, OH 44307, United States
Miguel Regueiro, Dalbir S Sandhu, Department of Gastroenterology, Hepatology and Nutrition, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH 44307, United States
Author contributions: Cha MH, Regueiro M, and Sandhu DS contributed equally to all aspects of the work.
Conflict-of-interest statement: The authors declare no conflicts of interest pertaining to this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Dalbir S Sandhu, MD, Assistant Professor, Director of Endoscopy, Department of Gastroenterology, Hepatology and Nutrition, Cleveland Clinic, Akron General, 1 Akron General Ave, Akron, OH 44307, United States.
Received: April 10, 2020
Peer-review started: April 10, 2020
First decision: April 18, 2020
Revised: April 25, 2020
Accepted: May 16, 2020
Article in press: May 16, 2020
Published online: May 21, 2020
Core Tip

Core tip: The coronavirus disease-2019 (COVID-19) pandemic, caused by the novel coronavirus termed severe acute respiratory syndrome coronavirus 2, is rapidly gripping the world. COVID-19 can cause a wide spectrum of disease, ranging from mild to severe symptoms and even death. Despite initial reports of the disease primarily presenting with respiratory symptoms, a surge in patients presenting with gastrointestinal symptoms is being reported. This review provides a detailed knowledge on gastrointestinal and hepatic manifestations of COVID-19.