Efficacy of bevacizumab-containing chemotherapy in metastatic colorectal cancer and CXCL5 expression: Six case reports
Apolonia Novillo, Department of Pre-clinical Dentistry, Health Sciences Faculty, Universidad Europea de Madrid, Villaviciosa de Odón, Madrid 28670, Spain
María Gaibar, Laura Beltrán, Miguel Galán, Department of Health Sciences, Health Sciences Faculty, Universidad Europea de Madrid, Villaviciosa de Odón, Madrid 28670, Spain
Alicia Romero-Lorca, María Fuencisla Gilsanz, Ana Fernández-Santander, Department of Medicine, Health Sciences Faculty, Universidad Europea de Madrid, Villaviciosa de Odón, Madrid 28670, Spain
Beatriz Antón, Diego Malón, Department of Oncology, University Hospital of Fuenlabrada, Fuenlabrada, Madrid 28942, Spain
Amalia Moreno, Department of Pathological Anatomy, University Hospital of Fuenlabrada, Fuenlabrada, Madrid 28942, Spain
Author contributions: Fernández-Santander A wrote the project to obtain funding, managed meetings between the university and hospital, reviewed the literature and drafted the manuscript; Malón D and Antón B were the patients' oncologists, reviewed the literature and contributed to manuscript drafting; Moreno A was responsible for paraffinating biopsy specimens and obtaining cuts; Galán M, Beltrán L and Gilsanz MF performed RNA isolation and purification procedure and reviewed the literature; Novillo A, Romero-Lorca A and Gaibar M conducted the genetic expression analysis and revised the intellectual content of the manuscript; all authors issued their final approval of the version to be submitted.
Supported by University Hospital of Fuenlabrada, Universidad Europea de Madrid (project numbers 2015/UEM12 and 2016/UEM13) and Fundación de la Universidad Europea (project numbers FGUE001804 and FGUE001805).
Informed consent statement: Informed written consent was obtained from the patients for publication of this report.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Ana Fernández-Santander, PhD, Full Professor, Research Scientist, Senior Researcher, Department of Medicine, Health Sciences Faculty, Universidad Europea de Madrid, Tajo, Villaviciosa de Odón, Madrid 28670, Spain. email@example.com
Received: January 7, 2020
Peer-review started: January 7, 2020
First decision: February 19, 2020
Revised: March 26, 2020
Accepted: April 17, 2020
Article in press: April 17, 2020
Published online: April 28, 2020