Iron metabolism imbalance at the time of listing increases overall and infectious mortality after liver transplantation
Elodie Fallet, Amandine Landrieux, Pauline Houssel-Debry, Caroline Jezequel, Ludivine Legros, Thomas Uguen, Dominique Guyader, Edouard Bardou-Jacquet, Service des Maladies du Foie, CHU Rennes, University Rennes, Rennes 35033, France
Michel Rayar, Pauline Houssel-Debry, Karim Boudjema, Service de Chirurgie Hepatobilaire, CHU Rennes, University Rennes, Rennes 35033, France
Christophe Camus, Service de Réanimation médicale, CHU Rennes, University Rennes, Rennes 35033, France
Martine Ropert-Bouchet, Laboratoire de biochimie, CHU Rennes, University Rennes, Rennes 35033, France
Author contributions: Bardou-Jacquet E contributed to study design and supervision; Fallet E and Bardou-Jacquet E drafted the manuscript; Fallet E, Uguen T and Rayar M gathered the Data; Bardou-Jacquet E and Rayar M performed statistical analysis; Landrieux A, Camus C, Houssel-Debry P, Jezequel C and Legros L managed the patients; all authors critically revised the manuscript.
Institutional review board statement: This study was approved by the Rennes University Ethics Committee on the 20th of October 2015.
Informed consent statement: According to this law (Loi Jardé n° 2012-300 the 5th of March 2012) the retrospective use of clinical and biological data generated during the routine car of patient does not require signed informed consent for patients included in this kind of study.
Conflict-of-interest statement: Authors have no conflict of interest to declare.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Edouard Bardou-Jacquet, MD, PhD, Professor of Medicine, Service des Maladies du Foie, CHU Rennes, University Rennes, CIC1414, Rennes 35033, France. email@example.com
Received: December 30, 2019
Peer-review started: December 30, 2019
First decision: January 19, 2020
Revised: March 30, 2020
Accepted: April 17, 2020
Article in press: April 17, 2020
Published online: April 28, 2020