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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 14, 2020; 26(10): 1098-1106
Published online Mar 14, 2020. doi: 10.3748/wjg.v26.i10.1098
Published online Mar 14, 2020. doi: 10.3748/wjg.v26.i10.1098
Is aggressive intravenous fluid resuscitation beneficial in acute pancreatitis? A meta-analysis of randomized control trials and cohort studies
Mohamed M Gad, Internal Medicine Department, Medicine Institute, Cleveland Clinic, Cleveland, OH 44195, United States
C. Roberto Simons-Linares, Gastroenterology and Hepatology Department, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH 44195, United States
Author contributions: Simons-Linares CR has formulated the concept/study idea, study design, review literature, manuscript drafting, writing; Gad MM has review the literature, contributed to metaanalysis design, statistical support, and manuscript drafting.
Conflict-of-interest statement: The authors deny any conflict of interest.
PRISMA 2009 Checklist statement: This is study followed PRISMA guidelines.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: C. Roberto Simons-Linares, MD, MSc, Assistant Professor, Gastroenterology and Hepatology Department, Digestive Disease Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, United States. robertosimons@outlook.com
Received: October 4, 2019
Peer-review started: October 4, 2019
First decision: November 4, 2019
Revised: January 12, 2020
Accepted: February 21, 2020
Article in press: February 21, 2020
Published online: March 14, 2020
Peer-review started: October 4, 2019
First decision: November 4, 2019
Revised: January 12, 2020
Accepted: February 21, 2020
Article in press: February 21, 2020
Published online: March 14, 2020
Core Tip
Core tip: Early aggressive intravenous fluid therapy did not improve mortality of acute pancreatitis patients and could potentially be harmful. The intravenous fluid therapy strategy in acute pancreatitis patients remains to be elucidated.