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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 21, 2019; 25(35): 5344-5355
Published online Sep 21, 2019. doi: 10.3748/wjg.v25.i35.5344
Published online Sep 21, 2019. doi: 10.3748/wjg.v25.i35.5344
Feasibility of endoscopic treatment and predictors of lymph node metastasis in early gastric cancer
Yu-Ning Chu, Ya-Nan Yu, Xue Jing, Tao Mao, Xian-Zhi Zhao, Zi-Bin Tian, Department of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong Province, China
Yun-Qing Chen, Department of Pathology, the Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong Province, China
Xiao-Bin Zhou, Department of Epidemiology and Health Statistics, School of Public Health, Qingdao University, Qingdao 266021, Shandong Province, China
Wen Song, Endoscopy Center, the Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong Province, China
Author contributions: Chu YN, Tian ZB, and Mao T contributed to study conception and design; Chu YN, Son W, Zhao XZ, and Chen YQ collected the data; Chu YN, Jing X, Zhou XB, and Yu YN analyzed and interpreted the data; Zhou XB reviewed the statistical methods and analysis; Chu YN wrote the manuscript; Tian ZB, Jing X, and Yu YN made the critical revision of the article.
Supported by the National Natural Science Foundation of China , No. 81502025 ; and the China Postdoctoral Science Foundation , No. 2018M632631 .
Institutional review board statement: This study was approved by the Institutional Review Board of the Ethics Committee of the Affiliated Hospital of Qingdao University.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All authors declare no conflicts of interest related to this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Zi-Bin Tian, MD, Director, Professor, Department of Gastroenterology, the Affiliated Hospital of Qingdao University, No. 16, Jiangsu Road, Qingdao 266003, Shandong Province, China. tianzbsun@163.com
Telephone: +86-532-82911302 Fax: +86-532-82911302
Received: July 12, 2019
Peer-review started: July 15, 2019
First decision: August 18, 2019
Revised: August 28, 2019
Accepted: September 9, 2019
Article in press: September 9, 2019
Published online: September 21, 2019
Peer-review started: July 15, 2019
First decision: August 18, 2019
Revised: August 28, 2019
Accepted: September 9, 2019
Article in press: September 9, 2019
Published online: September 21, 2019
Core Tip
Core tip: We aimed to re-evaluate and verify the current indications and guidelines for endoscopic treatment and to analyze the clinicopathological predictors of lymph node metastasis in early gastric cancer (EGC), which have been inconsistently identified across studies. To the best of our knowledge, this study involves the largest number of EGC patients in China, and is the first study to perform statistical analyses on certain clinical features, such as drinking, smoking, obesity, family history of tumors, and tumor markers.