Published online Jul 7, 2019. doi: 10.3748/wjg.v25.i25.3183
Peer-review started: March 18, 2019
First decision: April 4, 2019
Revised: May 2, 2019
Accepted: May 31, 2019
Article in press: June 1, 2019
Published online: July 7, 2019
Core tip: Africa has the highest rates of global prevalence of Helicobacter pylori (H. pylori) infection worldwide. Nevertheless, scarce data are available, describing in some cases both inappropriate diagnostic approaches and therapeutic regimens. This probably depends on the lack of continental consensus guideline for the management of H. pylori infection. As a consequence, there is an increasing number of papers reporting, in several countries, a high rate of bacterial resistance to the most commonly used antibiotics for H. pylori treatment. This manuscript gives an update on the African literature about H. pylori infection and on the present and future challenges in this context.