Beneficial effect of probiotics supplements in reflux esophagitis treated with esomeprazole: A randomized controlled trial
Qing-Hua Sun, Department of Gastroenterology, Peking University Third Hospital, Beijing 100191, China
Hong-Yan Wang, Shi-Dong Sun, Xin Zhang, Han Zhang, Department of Gastroenterology, PKUCare Luzhong Hospital, Zibo 255400, Shandong Province, China
Author contributions: Sun SD designed the research; Wang HY, Zhang X, and Zhang H performed the research; Sun SD and Wang HY contributed new reagents and analytic tools; Wang HY analyzed the data; Sun QH wrote the paper.
Supported by Shandong Provincial Medical and Health Technology Development Project, No. 2014ws0020.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of PKUCare Luzhong Hospital [2015-KY-003].
Clinical trial registration statement: This study is registered on the Chinese Clinical Trial Registry (No. ChiCTR1800018218).
Informed consent statement: All study participants, or their legal guardian, provided written informed consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: No additional data.
CONSORT 2010 statement: CONSORT 2010 checklist of information to include when reporting a randomized trial has been completed.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Shi-Dong Sun, Director, Vice President of Hospital, Department of Gastroenterology, PKUCare Luzhong Hospital, No. 65, Taigong Road, Linzi District, Zibo 255400, Shandong Province, China. sunshidong@163.com
Telephone: +86-533-7698006 Fax: +86-533-7698019
Received: January 11, 2019
Peer-review started: January 11, 2019
First decision: January 30, 2019
Revised: February 15, 2019
Accepted: February 22, 2019
Article in press: February 23, 2019
Published online: May 7, 2019
