Performance of tacrolimus in hospitalized patients with steroid-refractory acute severe ulcerative colitis
Peter Hoffmann, Cyrill Wehling, Jan Pfeiffenberger, Nina Belling, Annika Gauss, Department of Gastroenterology and Hepatology, Heidelberg University Hospital, Heidelberg 69120, Germany
Johannes Krisam, Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg 69120, Germany
Author contributions: Hoffmann P and Gauss A collected and analyzed the data; Gauss A wrote the manuscript; Wehling C, Pfeiffenberger J, and Belling N helped with data analyses and interpretation; Krisam J assisted with statistical analyses; all authors critically reviewed the manuscript and approved of its contents.
Institutional review board statement: The study was reviewed and approved by the Heidelberg University Institutional Review Board.
Informed consent statement: The requirement for informed consent was waived due to the retrospective nature of the study.
Conflict-of-interest statement: None declared.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Annika Gauss, MD, Assistant Professor, Department of Gastroenterology and Hepatology, Heidelberg University Hospital, Im Neuenheimer Feld 410, Heidelberg 69120, Germany. email@example.com
Telephone: +49-6221568705 Fax: +49-6221565255
Received: February 14, 2019
Peer-review started: February 14, 2019
First decision: February 21, 2019
Revised: February 23, 2019
Accepted: March 11, 2019
Article in press: March 12, 2019
Published online: April 7, 2019