Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 28, 2019; 25(12): 1445-1456
Published online Mar 28, 2019. doi: 10.3748/wjg.v25.i12.1445
Growing burden of alcoholic liver disease in China: A review
Wen-Jun Wang, Peng Xiao, Hong-Qin Xu, Jun-Qi Niu, Yan-Hang Gao
Wen-Jun Wang, Peng Xiao, Hong-Qin Xu, Jun-Qi Niu, Yan-Hang Gao, Department of Hepatology, First Hospital of Jilin University, Jilin University, Changchun 130021, Jilin Province, China
Author contributions: Gao YH and Niu JQ designed the research; Wang WJ and Xiao P performed the data analyses; Gao YH and Wang WJ drafted the manuscript; Gao YH and Xu HQ revised the paper; All authors approved the final version.
Supported by the National Science and Technology Major Project, No. 2017ZX10202202 and No. 2018ZX10302206; the National Key Research Plan "Precision Medicine Research" Key Project, No. 2017YFC0908103; the National Natural Science Foundation of Jilin Province, No. 20160101097JC; the Program for JLU Science and Technology Innovative Research Team, No. 2017TD-08; and the Fundamental Research Funds for the Central Universities.
Conflict-of-interest statement: The authors have no potential conflicts of interest and received no financial support.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Yan-Hang Gao, MD, PhD, Chief Doctor, Department of Hepatology, First Hospital of Jilin University, Jilin University, No. 71, Xinmin Street, Changchun 130021, Jilin Province, China.
Telephone: +86-431-81875121 Fax: +86-431-81875106
Received: January 24, 2019
Peer-review started: January 24, 2019
First decision: February 13, 2019
Revised: February 22, 2019
Accepted: March 1, 2019
Article in press: March 2, 2019
Published online: March 28, 2019
Core Tip

Core tip: Explosive economic growth and increasing social openness in China over the last 30 years have significantly boosted alcohol consumption, and consequently, the incidence of alcoholic liver disease (ALD) in China has increased. This review describes the epidemiology, pathogenesis, genetic polymorphisms, diagnosis, and treatment of ALD in the Chinese population, with the goal of supporting the development of useful strategies for reducing the global ALD burden.