Inhibitory effects of patchouli alcohol on stress-induced diarrhea-predominant irritable bowel syndrome
Tian-Ran Zhou, Jing-Jing Huang, Zi-Tong Huang, Bo Tan, The Research Center for Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, Guangdong Province, China
Hong-Ying Cao, School of Chinese Materia Medica, Guangzhou University of Chinese Medicine, Guangzhou 510006, Guangdong Province, China
Author contributions: Zhou TR participated in the design of the study, performed the experiments, statistical analysis and drafted the manuscript; Tan B and Cao HY participated in the design of the research and helped to draft the manuscript; Huang JJ and Huang ZT assisted in the performance and the recording of experiments. All the authors have read and approved the submission of manuscript.
Supported by the National Natural Science Foundation of China, No. 81573715; Natural Science Foundation of Guangdong Province, China, No. 2015A030313348; and Science and Technology Program of Guangzhou, China, No. 201510010257.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Guangzhou University of Chinese Medicine, Guangzhou, China.
Institutional animal care and use committee statement: All procedures involving animals were reviewed and approved by the Institutional Animal Care and Use Committee of Guangzhou University of Chinese Medicine (IACUC protocol number: ).
Conflict-of-interest statement: The authors declare that there is no conflict of interest exists in this study.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Bo Tan, MD, PhD, Associate Professor, The Research Center for Integrative Medicine, School of Fundamental Medical Sciences, Guangzhou University of Chinese Medicine, 233 Waihuan Dong Rd, Guangzhou 510006, Guangdong Province, China. firstname.lastname@example.org
Received: September 14, 2017
Peer-review started: September 14, 2017
First decision: October 24, 2017
Revised: November 6, 2017
Accepted: November 28, 2017
Article in press: November 28, 2017
Published online: February 14, 2018