Different distributions of interstitial cells of Cajal and platelet-derived growth factor receptor-α positive cells in colonic smooth muscle cell/interstitial cell of Cajal/platelet-derived growth factor receptor-α positive cell syncytium in mice
Chen Lu, Xu Huang, Hong-Li Lu, Yu-Jia Li, Wen-Xie Xu, Department of Physiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China
Shao-Hua Liu, Department of Anesthesiology, Ren Ji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 201112, China
Jing-Yu Zang, Jie Chen, Department of Pediatric Surgery, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
Author contributions: Lu C designed and performed the majority of experiments; Huang X, Lu HL, and Liu SH contributed new reagents and analytic tools; Zang JY, Li YJ, and Chen J analyzed the data; Xu WX wrote and edited the manuscript.
Supported by The National Natural Science Foundation of China, No. 31671192 and No. 31571180; and Foundation of Xin Hua Hospital, No. JZPI201708.
Institutional review board statement: This research was approved by the Ethics Committee of Shanghai Jiao Tong University School of Medicine.
Institutional animal care and use committee statement: The protocol was approved by the Committee on the Ethics of Animal Experiments of Shanghai Jiao Tong University School of Medicine (Permit Number: Hu 686-2009).
Conflict-of-interest statement: To the best of our knowledge, no conflict of interest exists.
Data sharing statement: No additional data is available.
ARRIVE guidelines statement: The authors have read the ARRIVE guidelines and prepared the manuscript accordingly.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author to: Wen-Xie Xu, PhD, Professor, Department of Physiology, Shanghai Jiao Tong University School of Medicine, 800 Dongchuan Road, Shanghai 200240, China. email@example.com
Telephone: +86-21-34205639 Fax: +86-21-34205639
Received: August 24, 2018
Peer-review started: August 24, 2018
First decision: October 5, 2018
Revised: November 7, 2018
Accepted: November 7, 2018
Article in press: November 7, 2018
Published online: November 28, 2018