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World J Gastroenterol. Oct 14, 2018; 24(38): 4330-4340
Published online Oct 14, 2018. doi: 10.3748/wjg.v24.i38.4330
Towards hepatitis C virus elimination: Egyptian experience, achievements and limitations
Dalia Omran, Mohamed Alboraie, Rania A Zayed, Mohamed-Naguib Wifi, Mervat Naguib, Mohamed Eltabbakh, Mohamed Abdellah, Ahmed Fouad Sherief, Sahar Maklad, Heba Hamdy Eldemellawy, Omar Khalid Saad, Doaa Mohamed Khamiss, Mohamed El Kassas
Dalia Omran, Department of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Cairo 11651, Egypt
Mohamed Alboraie, Mohamed Abdellah, Department of Internal Medicine, Al-Azhar University, Cairo 11651, Egypt
Rania A Zayed, Department of Clinical and Chemical Pathology, Faculty of Medicine, Cairo University, Cairo 11651, Egypt
Mohamed-Naguib Wifi, Mervat Naguib, Department of Internal Medicine, Faculty of Medicine, Cairo University, Cairo 11599, Egypt
Mohamed Eltabbakh, Ahmed Fouad Sherief, Department of Tropical Medicine, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt
Sahar Maklad, National Hepatology and Tropical Medicine Research Institute, Cairo 11599, Egypt
Heba Hamdy Eldemellawy, Department of Internal Medicine, Faculty of Medicine, Beni-Suef University, Beni-Suef 62511, Egypt
Omar Khalid Saad, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt
Doaa Mohamed Khamiss, Department of Clinical and Chemical Pathology, El-monera hospital, Ministry of Health, Cairo 11562, Egypt
Mohamed El Kassas, Department of Endemic Medicine, Faculty of Medicine, Helwan University, Cairo 11599, Egypt
Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision, editing, and final approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dalia Omran, MD, Professor, Department of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Egypt. daliaomran@kasralainy.edu.eg
Telephone: +20-10-00087802 Fax: +20-2-23682030
Received: March 27, 2018
Peer-review started: March 27, 2018
First decision: April 3, 2018
Revised: September 13, 2018
Accepted: October 5, 2018
Article in press: October 5, 2018
Published online: October 14, 2018
Core Tip

Core tip: Egypt started a large treatment program intended to provide therapy for Egyptian hepatitis C virus (HCV)-infected patients. The Egyptian National Committee for the Control of Viral Hepatitis provides a model of care that could help other countries with high HCV prevalence rate in their battle against HCV. This review covers the results of HCV management in Egyptian real life settings and the outcome of different treatment protocols. Also, it covers the current and future strategies for HCV prevention and screening. Lastly, we discussed the challenges facing HCV elimination and the prospect of future eradication of HCV.