Case Report
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 14, 2018; 24(34): 3958-3964
Published online Sep 14, 2018. doi: 10.3748/wjg.v24.i34.3958
Unicentric Castleman disease presenting as a retroperitoneal peripancreatic mass: A report of two cases and review of literature
Jia-Lin Cheng, Jing Cui, Yi Wang, Zong-Zhen Xu, Feng Liu, Shu-Bin Liang, Hu Tian
Jia-Lin Cheng, Shu-Bin Liang, Taishan Medical University, Tai’an 271016, Shandong Province, China
Jia-Lin Cheng, Zong-Zhen Xu, Feng Liu, Shu-Bin Liang, Hu Tian, Department of General Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, Shandong Province, China
Jing Cui, Department of Pathology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, Shandong Province, China
Yi Wang, Department of Medical Imaging, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, Shandong Province, China
Author contributions: Cheng JL designed the report and wrote the paper; Cheng JL, Xu ZZ, Liu F and Tian H performed the surgery; Cheng JL, Cui J, Wang Y and Liang SB collected the patient’s clinical data; Cheng JL and Tian H analyzed the data and revised the paper; all authors have read and approved the final version of this manuscript.
Supported by the Key Research and Development Plan of Shandong Province, No. 2016GSF201108.
Informed consent statement: The patients included in this study gave written informed consent for the use and disclosure of their protected health information.
Conflict-of-interest statement: The authors of this manuscript have no conflicts of interest to disclose.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hu Tian, MD, PhD, Chief Doctor, Professor, Surgeon, Department of General Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, No. 16766, Jingshi Road, Jinan 250014, Shandong Province, China. tianhu6585@163.com
Telephone: +86-531-89269817 Fax: +86-531-82963647
Received: April 23, 2018
Peer-review started: April 27, 2018
First decision: July 4, 2018
Revised: July 10, 2018
Accepted: July 22, 2018
Article in press: July 22, 2018
Published online: September 14, 2018
Core Tip

Core tip: We report two typical cases of unicentric Castleman disease (UCD) presenting as a retroperitoneal peripancreatic mass. The clinical manifestations and imaging findings of these masses were nonspecific. UCD is difficult to diagnose prior to surgery, and the diagnosis is mainly by postoperative pathological examination. The occurrence of UCD in the abdominal cavity is very rare, especially in the retroperitoneal peripancreatic region. Importantly, both patients recovered well without postoperative radiochemotherapy. These case reports provide a valuable reference for the diagnosis and treatment of this disease.