Case Report
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 7, 2018; 24(33): 3806-3812
Published online Sep 7, 2018. doi: 10.3748/wjg.v24.i33.3806
Neurofibromatosis type 1-associated multiple rectal neuroendocrine tumors: A case report and review of the literature
Rui Xie, Kuang-I Fu, Shao-Min Chen, Bi-Guang Tuo, Hui-Chao Wu
Rui Xie, Kuang-I Fu, Shao-Min Chen, Bi-Guang Tuo, Hui-Chao Wu, Department of Gastroenterology, Affiliated Hospital to Zunyi Medical College, Zunyi 563003, Guizhou Province, China
Kuang-I Fu, Department of Endoscopy, Kanma Memorial Hospital, Tokyo 3250046, Japan.
Author contributions: Tuo BG and Wu HC are the co-corresponding authors; Xie R and Chen SM managed patients and collected data; Xie R was in charge of pathological examination; Fu KI, Tuo BG and Wu HC were responsible for case design and writing.
Informed consent statement: Written informed consent was obtained.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hui-Chao Wu, PhD, Full Professor, Department of Gastroenterology, Affiliated Hospital to Zunyi Medical College, Zunyi 563003, Guizhou Province, China. wuhui-chao_gzzy@aliyun.com
Telephone: +86-851-28609206 Fax: +86-851-28609205
Received: May 18, 2018
Peer-review started: May 18, 2018
First decision: June 6, 2018
Revised: June 11, 2018
Accepted: July 21, 2018
Article in press: July 21, 2018
Published online: September 7, 2018
Core Tip

Core tip: Neurofibromatosis type 1 (NF-1) is commonly complicated with either benign or malignant tumors in both the central and peripheral nervous systems. However, there are rare reported cases of NF-1 associated with multiple rectal neuroendocrine tumors. This study reports a case of a 39 year old female NF-1 patient with not only multiple rectal neuroendocrine neoplasms but also vascular malformations and scoliosis.