Post-polypectomy bleeding and thromboembolism risks associated with warfarin vs direct oral anticoagulants
Naohiro Yanagisawa, Naoyoshi Nagata, Kazuhiro Watanabe, Tatsuhiro Iida, Mariko Hamada, Sakurako Kobayashi, Junichi Akiyama, Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Tokyo 162-8655, Japan
Takuro Shimbo, Ohta Nishinouchi Hospital, Fukushima 963-8022, Japan
Naomi Uemura, Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Kohnodai Hospital, Chiba 272-8516, Japan
Author contributions: Yanagisawa N collected the clinical data and drafted the manuscript; Nagata N designed the study and is equally a first author; Shimbo T was responsible for statistical analysis; Yanagisawa N, Iida T, Hamada M and Kobayashi S performed data collection and are the main authors of the manuscript; Watanabe K and Akiyama J assisted with treatment; Akiyama J and Uemura N edited the manuscript; all authors read and approved the submitted version of the manuscript.
Supported by Grant-in-Aid for Research from the National Center for Global Health and Medicine (29-2001) partly. The funding agency played no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Institutional review board statement: The study design was approved by the ethics committee of the National Center for Global Health and Medicine (Approval No. 2176).
Informed consent statement: This study was a retrospective observational study, and informed consent to participate was obtained by the opt-out method at our institution.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Naoyoshi Nagata, MD, PhD, Doctor, Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan. firstname.lastname@example.org
Telephone: +81-3-32027181 Fax: +81-3-32071038
Received: February 20, 2018
Peer-review started: February 21, 2018
First decision: March 9, 2018
Revised: March 15, 2018
Accepted: March 25, 2018
Article in press: March 25, 2018
Published online: April 14, 2018