Retrospective Study
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 21, 2018; 24(11): 1250-1258
Published online Mar 21, 2018. doi: 10.3748/wjg.v24.i11.1250
Epidemiological features of chronic hepatitis C infection caused by remunerated blood donors: A nearly 27-year period survey
You-Wen Tan, Yan Tao, Long-Gen Liu, Yun Ye, Xin-Bei Zhou, Li Chen, Cong He
You-Wen Tan, Yan Tao, Yun Ye, Xin-Bei Zhou, Li Chen, Cong He, Department of Hepatology, The Third Hospital of Zhenjiang Affiliated Jiangsu University, Zhenjiang 212003, Jiangsu Province, China
Long-Gen Liu, Department of Hepatology, The Third People’s Hospital of Changzhou, Changzhou 213001, Jiangsu Province, China
Author contributions: Tan YW, Tao Y and Liu LG contributed equally to this work; Tan YW designed the research; Tao Y, Ye Y, Zhou XB, Chen L, He C and Liu LG collected and analyzed the data and drafted the manuscript; Tao Y and Ye Y performed the research; Ye Y and He C interpreted the data and revised the statistical analysis; Tan YW and Tao Y wrote and revised the article; all authors have read and approved the final version to be published.
Supported by the Preventive Medicine research projects of Jiangsu Province, No. Y2012016; and the Social Development Project of Zhenjiang City, No. SH2014060. The funders had no role in study design, data collection and analysis, nor decision to publish.
Institutional review board statement: The study was reviewed and approved for publication by our Institutional Reviewer.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: To the best of our knowledge, no conflict of interest exists.
Data sharing statement: The original anonymous dataset is available upon request from the corresponding author at
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: You-Wen Tan, PhD, Attending Doctor, Chief Doctor, Department of Hepatology, The Third Hospital of Zhenjiang Affiliated Jiangsu University No. 300, Daijiamen, Runzhou Distinct, Zhenjiang 212003, Jiangsu Province, China.
Telephone: +86-13914567088 Fax: +86-511-88970796
Received: January 9, 2018
Peer-review started: January 9, 2018
First decision: January 25, 2018
Revised: February 1, 2018
Accepted: February 9, 2018
Article in press: February 9, 2018
Published online: March 21, 2018
Core Tip

Core tip: A retrospective and cross-sectional study was conducted. A total of 1694 participants were investigated and categorized into three groups: 2 (3.3%), 534 (68.5%), and 324 (58.8%) patients positive for anti-hepatitis C virus (HCV) in blood donor, single plasma donor, and mixed donor groups, respectively. A total of 592 (68.05%) cases had detectable HCV RNA, and genotype 1b accounted for 91.9%. A total of 161 (27.2%, 161/592) patients with chronic HCV were considered to have cirrhosis with a liver stiffness measurement level of more than 12 kPa. Multiple logistic (binary) regression analysis results showed that platelet and IgG levels were associated with cirrhosis.