Retrospective Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 28, 2017; 23(8): 1443-1449
Published online Feb 28, 2017. doi: 10.3748/wjg.v23.i8.1443
Helicobacter pylori infection with intestinal metaplasia: An independent risk factor for colorectal adenomas
Ye Yan, Yi-Na Chen, Qian Zhao, Chao Chen, Chun-Jing Lin, Yin Jin, Shuang Pan, Jian-Sheng Wu
Ye Yan, Yi-Na Chen, Qian Zhao, Chao Chen, Yin Jin, Shuang Pan, Department of Gastroenterology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China
Chun-Jing Lin, Jian-Sheng Wu, Medical and Health Care Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China
Author contributions: Yan Y designed and performed the research and wrote the paper; Chen YN, Zhao Q, and Chen C collected the data and designed the research; Lin CJ, Jin Y, Pan S, and Wu JS provided clinical advice and supervised the report.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board and the Ethics Committee of The First Affiliated Hospital of Wenzhou Medical University.
Informed consent statement: The requirement for informed consent was waived because we retrospectively accessed de-identified data only.
Conflict-of-interest statement: The authors declare that there is no conflict of interest with the paper presented.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Jian-Sheng Wu, Professor, Medical and Health Care Center, The First Affiliated Hospital of Wenzhou Medical University, No. 1 Nan Bai Xiang street, Wenzhou 325000, Zhejiang Province, China. wzwujs@163.com
Telephone: +86-577-55578033 Fax: +86-577-55578033
Received: October 14, 2016
Peer-review started: October 19, 2016
First decision: December 2, 2016
Revised: December 14, 2016
Accepted: January 4, 2017
Article in press: January 4, 2017
Published online: February 28, 2017
Core Tip

Core tip: This retrospective study revealed Helicobacter pylori (H. pylori)-related intestinal metaplasia (IM) to be an independent risk factor for colorectal adenomas in Chinese individuals aged ≥ 40 years. Clinically, it may be useful for patients with H. pylori infection and IM to undergo colonoscopy screening and surveillance.