Clinical Trials Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 28, 2017; 23(44): 7875-7880
Published online Nov 28, 2017. doi: 10.3748/wjg.v23.i44.7875
Role of combined propofol and sufentanil anesthesia in endoscopic injection sclerotherapy for esophageal varices
Yang Yu, Sheng-Lin Qi, Yong Zhang
Yang Yu, Department of Anesthesiology, the Sixth People’s Hospital of Dalian, Dalian 116000, Liaoning Province, China
Sheng-Lin Qi, Endoscopy Center, the Sixth People’s Hospital of Dalian, Dalian 116000, Liaoning Province, China
Yong Zhang, President Office, the Sixth People’s Hospital of Dalian, Dalian 116000, Liaoning Province, China
Author contributions: Yu Y and Zhang Y designed research; Yu Y and Qi SL performed research and analyzed data; Yu Y wrote paper.
Institutional review board statement: The study was reviewed and approved by the The Sixth People’s Hospital of Dalian, Dalian, China.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: Not declared.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Yong Zhang, MD, President Office, the Sixth People’s Hospital, No. 269, Huibai Road, Dalian 116000, Liaoning Province, China.
Telephone: +86-13842880969 Fax: +86-411-39728555
Received: August 19, 2017
Peer-review started: August 19, 2017
First decision: August 29, 2017
Revised: September 4, 2017
Accepted: September 13, 2017
Article in press: September 13, 2017
Published online: November 28, 2017
Core Tip

Core tip: Propofol is widely used during painless endoscopy because of its rapid onset and rapid recovery properties. Intravenous injection of propofol during endoscopic esophageal varices therapy can reduce the complications associated with poor patient cooperation. Because of complications related to bleeding during endoscopic variceal ligation and endoscopic injection sclerotherapy (EIS), endotracheal intubation is essential for these procedures. However, due to its weak analgesic effect, intraoperative pain stimulation is greater, leading to overt physical movement, thus affecting the operation. Since analgesics are often required to ensure a successful operation, in this study, we used a combination of sufentanil and propofol injection for the endoscopic treatment of esophageal varices. In conclusion, sufentanil and propofol injection, with endotracheal intubation-assisted EIS is effective and safe.