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©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Development and validation of a simple and multifaceted instrument, GERD-TEST, for the clinical evaluation of gastroesophageal reflux and dyspeptic symptoms
Koji Nakada, Nobuyuki Matsuhashi, Katsuhiko Iwakiri, Atsushi Oshio, Takashi Joh, Kazuhide Higuchi, Ken Haruma
Koji Nakada, Department of Laboratory Medicine, Daisan Hospital Jikei University School of Medicine, Tokyo 201-8601, Japan
Nobuyuki Matsuhashi, Department of Gastroenterology, NTT Medical Center Tokyo, Tokyo 141-8625, Japan
Katsuhiko Iwakiri, Department of Gastroenterology, Nippon Medical School Graduate School of Medicine, Tokyo 113-0022, Japan
Atsushi Oshio, Faculty of Letters, Arts and Sciences, Waseda University, Tokyo 162-8644, Japan
Takashi Joh, Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan
Kazuhide Higuchi, Second Department of Internal Medicine, Osaka Medical College, Osaka 569-8686, Japan
Ken Haruma, Department of General Internal Medicine 2, Kawasaki Medical School Kawasaki Hospital, Kurashiki 701-0192, Japan
Author contributions: Nakada K, Iwakiri K, Joh T, Higuchi K and Haruma K designed the study; Matsuhashi N and other physicians listed in the acknowledgments collected the data; Oshio A contributed to statistical analysis; Nakada K wrote the paper; all authors have read and approved the final version to be published.
Supported by Financial support for this clinical study was provided by GERD Society (Osaka, Japan).
Institutional review board statement: This study was approval by the ethics committee of each institution or the central ethics committee of Nishi Clinic, Osaka, Japan.
Informed consent statement: Written informed consent was obtained from all enrolled patients.
Clinical trial registration statement: This study was registered with the University Hospital Medical Information Network’s Clinical Trials Registry (UMIN-CTR; registration number 000006614).
Conflict-of-interest statement: The authors declare no conflicts of interests related to the publication of this study.
Data sharing statement: No additional data was available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Koji Nakada, MD, PhD, Associate Professor, Department of Laboratory Medicine, Daisan Hospital Jikei University School of Medicine, 4-11-1, Izumihoncyo, Komae-shi, Tokyo 201-8601, Japan. nakada@jikei.ac.jp
Telephone: +81-3-34801151-3401 Fax: +81-3-34805700
Received: March 6, 2017
Peer-review started: March 7, 2017
First decision: April 25, 2017
Revised: June 11, 2017
Accepted: June 19, 2017
Article in press: June 19, 2017
Published online: July 28, 2017
