Observational Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 14, 2017; 23(26): 4815-4822
Published online Jul 14, 2017. doi: 10.3748/wjg.v23.i26.4815
Extreme liver resections with preservation of segment 4 only
Silvio Marcio Pegoraro Balzan, Vinícius Grando Gava, Marcelo Arbo Magalhães, Marcelo Luiz Dotto
Silvio Marcio Pegoraro Balzan, Marcelo Arbo Magalhães, Marcelo Luiz Dotto, Department of Pharmacy and Biology, University of Santa Cruz do Sul, 96810-110 Santa Cruz do Sul, Brazil
Silvio Marcio Pegoraro Balzan, Vinícius Grando Gava, Department of Surgery, Hospital Moinhos de Vento, 90035 Porto Alegre, Brazil
Author contributions: Balzan SMP, Gava VG and Magalhães MA designed the research, treated the patients, collected and analyzed the data, and wrote the paper; Dotto ML treated the patients and wrote the paper; all authors read and approved the final version for publication.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Hospital Ana Nery.
Conflict-of-interest statement: All authors declare no conflict of interest in relation to this study or its publication.
Data sharing statement: Technical appendix, statistical code and dataset are available from the corresponding author at sbalzan@hotmail.com. The data were anonymized and, thus, informed consent was not required from the participants.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Silvio Marcio Pegoraro Balzan, PhD, Department of Pharmacy and Biology, University of Santa Cruz do Sul, Rua Marechal Deodoro, 1139, 96810-110 Santa Cruz do Sul, Brazil. silviobalzan@unisc.br
Telephone: +55-51-37152824 Fax: +55-51-37152824
Received: January 29, 2017
Peer-review started: February 8, 2017
First decision: March 16, 2017
Revised: May 3, 2017
Accepted: June 9, 2017
Article in press: June 12, 2017
Published online: July 14, 2017
Core Tip

Core tip: Extreme hepatic resections with preservation of one segment only may be required for complete resection of multiple bilobar liver metastases. We evaluated a new technique of two-stage hepatectomy with preservation of segment 4 only. Stage one involves a right hepatectomy with middle hepatic vein preservation and associated left lobe congestion through reduction of the left hepatic vein diameter. This combination optimizes segment 4 regeneration while allowing the left lobe (to be resected) to maintain function with reduced hypertrophy. Stage two involves a left lobectomy. Hypertrophy rates of non-congested segment 4 were significantly greater than in congested left lobe.