Retrospective Cohort Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 14, 2017; 23(26): 4752-4758
Published online Jul 14, 2017. doi: 10.3748/wjg.v23.i26.4752
Hospital costs, length of stay and prevalence of hip and knee arthroplasty in patients with inflammatory bowel disease
Eli D Ehrenpreis, Ying Zhou
Eli D Ehrenpreis, E2Bio Consultants, Evanston, IL 60201, United States
Ying Zhou, Research Institute, North Shore University Health System, Evanston, IL 60201, United States
Author contributions: Ehrenpreis ED was involved in the following portions of the study: Study design, data analysis, manuscript writing, manuscript revisions; Zhou Y was involved in the following portions of the study: Study design, data analysis, manuscript writing, manuscript revisions.
Institutional review board statement: The study was reviewed by North Shore University Health System Institutional Review Board and deemed appropriate for exempt status of Institutional Review Board oversight due to the de-identified nature of HCUP-NIS data.
Informed consent statement: The clinical data utilized in this study is de-identified and was obtained from a publicly available database. Therefore, informed consent was not required for this study.
Conflict-of-interest statement: The authors have no conflicts of interest related to this study to report.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Eli D Ehrenpreis, MD, AGAF, FACG, Medical Director, E2Bio Consultants, 2906 Central St, Evanston, IL 60201, United States.
Telephone: +1-847-6571900 Fax: +1-224-3647319
Received: January 26, 2017
Peer-review started: February 3, 2017
First decision: March 29, 2017
Revised: May 15, 2017
Accepted: June 18, 2017
Article in press: June 19, 2017
Published online: July 14, 2017
Core Tip

Core tip: Patients with inflammatory bowel disease (IBD) have predisposing risk factors for arthroplasty of the hip and possibly the knee. IBD patients are also at higher risk for thromboembolic events, and longer and more complex hospitalizations for non-intestinal surgeries. Despite these considerations, this study of the National Inpatient Survey, the largest publicly available inpatient healthcare database in the United States, demonstrates the unexpected findings that patients with IBD have similar costs, lengths of stay and mortality when hospitalized for hip and knee arthroplasties. In addition, these surgeries are significantly less prevalent in patients with IBD than the general population.