Retrospective Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 7, 2016; 22(9): 2828-2836
Published online Mar 7, 2016. doi: 10.3748/wjg.v22.i9.2828
Early complications after interventions in patients with acute pancreatitis
Ai-Lin Wei, Qiang Guo, Ming-Jun Wang, Wei-Ming Hu, Zhao-Da Zhang
Ai-Lin Wei, Qiang Guo, Ming-Jun Wang, Wei-Ming Hu, Zhao-Da Zhang, Department of Pancreatic Surgery, West China Hospital, Chengdu 610041, Sichuan Province, China
Author contributions: Wei AL, Guo Q, Hu WM and Zhang ZD conceived and designed the study; Wei AL and Wang MJ performed the study; Wei AL and Guo Q analyzed the data; Wei AL wrote the paper; all authors have read and approved the final version to be published.
Institutional review board statement: The study was reviewed and approved by the West China Hospital of Sichuan University Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors declare no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Zhao-Da Zhang, MD, Department of Pancreatic Surgery, West China Hospital, No. 37, Guoxue Alley, Chengdu 610041, Sichuan Province, China.
Telephone: +86-28-85422474 Fax: +86-28-85422872
Received: September 1, 2015
Peer-review started: September 1, 2015
First decision: October 15, 2015
Revised: November 4, 2015
Accepted: November 24, 2015
Article in press: November 24, 2015
Published online: March 7, 2016
Core Tip

Core tip: Intra-abdominal bleeding, colonic fistula, and progressive infection are the three major early post-procedural complications in patients with acute necrotizing pancreatitis regardless of the selected approach. Possible predictors, accurate diagnosis, and appropriate management methods are beneficial to decrease the mortality rate and convalescence, as well as promote the life quality of patients with acute pancreatitis. In this study, Marshall score, organ failures, preoperative respiratory infection, sepsis, preoperative systemic inflammatory response syndrome, and C-reactive protein level upon admission are associated with post-procedural complications. Proper and gentle intervention process, and close monitoring and evaluation of patients who are prone to suffer from postoperative complications may increase the therapeutic efficiency.