Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 28, 2016; 22(36): 8123-8136
Published online Sep 28, 2016. doi: 10.3748/wjg.v22.i36.8123
Inflammatory bowel disease in India - Past, present and future
Gautam Ray
Gautam Ray, Gastroenterology Unit, Department of Medicine, B.R.Singh Hospital, Kolkata 700014, West Bengal, India
Author contributions: Ray G gathered all data and wrote the manuscript.
Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Dr. Gautam Ray, Gastroenterology Unit, Department of Medicine, B.R.Singh Hospital, BB Ganguly Street, Kolkata 700014, West Bengal, India.
Telephone: +91-332-2658804 Fax: 91-332-3507003
Received: June 29, 2016
Peer-review started: June 30, 2016
First decision: July 29, 2016
Revised: August 9, 2016
Accepted: August 23, 2016
Article in press: August 23, 2016
Published online: September 28, 2016
Core Tip

Core tip: There is growing interest in inflammatory bowel disease (IBD) in India due to its rising incidence. This review addresses the current state of knowledge on different aspects of Indian IBD patients like epidemiology, genetics, mechanisms, clinical presentations and treatment (compared to other south Asian countries) in the context of which future areas of research is highlighted. The disease is milder in India. Well-designed population based studies are needed. To address the obscure pathogenesis and uncertain disease course (behaviour, activity, treatment response, development of cancer and prognosis) studies on mechanisms, biomarkers, advanced endoscopic techniques need to be done to decrease the morbidity burden.