Pretreatment AKR1B10 expression predicts the risk of hepatocellular carcinoma development after hepatitis C virus eradication
Ayato Murata, Takuya Genda, Nozomi Amano, Sho Sato, Hironori Tsuzura, Shunsuke Sato, Yutaka Narita, Yoshio Kanemitsu, Yuji Shimada, Katsuyori Iijima, Akihito Nagahara, Department of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Shizuoka 410-2295, Japan
Takafumi Ichida, Katsuharu Hirano, Department of Hepatology, Shonan-East General Hospital, Kanagawa 253-0083, Japan
Ryo Wada, Department of Pathology, Juntendo University Shizuoka Hospital, Shizuoka 410-2295, Japan
Sumio Watanabe, Department of Gastroenterology, Juntendo University School of Medicine, Tokyo 113-8431, Japan
Author contributions: Murata A, Genda T, Ichida T, Amano N, Sato S, Tsuzura H, Sato S, Narita Y, Kanemitsu Y, Shimada Y, Hirano K, Iijima K, Wada R, Nagahara A and Watanabe S designed the study; Murata A collected and analyzed the data; Murata A and Genda T wrote the paper; all authors have read and approved the final version to be published.
Supported by Grant-in-Aid from the Ministry of Health, Labor and Welfare of Japan.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Juntendo University Shizuoka Hospital.
Informed consent statement: Written informed consent was obtained from all the patients enrolled in the study.
Conflict-of-interest statement: The authors declare no conflict of interest related to this study.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Takuya Genda, MD, PhD, Associate Professor, Department of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni-shi, Shizuoka 410-2295, Japan. email@example.com
Telephone: +81-55-9483111 Fax: +81-55-9485088
Received: May 21, 2016
Peer-review started: May 23, 2016
First decision: June 20, 2016
Revised: July 4, 2016
Accepted: August 1, 2016
Article in press: August 1, 2016
Published online: September 7, 2016