Haemoxygenase modulates cytokine induced neutrophil chemoattractant in hepatic ischemia reperfusion injury
Niteen Tapuria, Sameer Junnarkar, Mahmoud Abu-amara, Barry Fuller, Alexander M Seifalian, Brian R Davidson, Department of HPB Surgery and Liver transplantation, Royal Free Hospital, London NW32QG, United Kingdom
Author contributions: Tapuria N performed the majority of experiments and wrote the manuscript; Junnarkar S helped with experiments and sample collection; Abu-amara M helped with analysis; Fuller B performed literature review; Seifalian AM coordinated the research; and Davidson BR supervised the research.
Supported by Peter Samuel Grant, Royal Free NHS trust United Kingdom.
Institutional review board statement: This study has been reviewed by the Royal Free research committee and approved.
Institutional animal care and use committee statement: All experiments were conducted under project license from home office United Kingdom in accordance with the animals’ scientific act 1986. All animals were treated in accordance with the guidelines issued by the home office.
Conflict-of-interest statement: No conflict of interest.
Data sharing statement: No additional data available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Niteen Tapuria, MS, MD (research), FRCS, FRCS (Gen Surg), Department of HPB Surgery and Liver transplantation, Royal Free Hospital, Hampstead, London NW32QG, United Kingdom. firstname.lastname@example.org
Received: September 27, 2015
Peer-review started: September 28, 2015
First decision: November 27, 2015
Revised: February 5, 2016
Accepted: May 21, 2016
Article in press: May 23, 2016
Published online: September 7, 2016