Increased duodenal expression of miR-146a and -155 in pediatric Crohn’s disease
Dániel Szűcs, Csaba Bereczki, Department of Pediatrics and Pediatric Health Care Center, University of Szeged, H-6725 Szeged, Hungary
Nóra Judit Béres, Zoltán Kiss, Réka Rokonay, Kriszta Boros, András Arató, Attila J Szabó, Gábor Veres, 1st Department of Pediatrics, Semmelweis University, H-1083 Budapest, Hungary
Katalin Borka, 2nd Department of Pathology, Semmelweis University, H-1091 Budapest, Hungary
Erna Sziksz, Attila J Szabó, Ádám Vannay, 1st Department of Pediatrics, Semmelweis University and MTA-SE Pediatrics and Nephrology Research Group, H-1083 Budapest, Hungary
Author contributions: Szűcs D was the gastroenterologist providing the mucosal biopsies for the study conducted by Bereczki C, Szűcs D, Béres NJ and Veres G designed the research; Arató A and Szabó AJ coordinated the research; Béres NJ, Kiss Z, Rokonay R and Boros K performed the research; Borka K performed the pathological evaluations of the biopsies; Szűcs D and Béres NJ analyzed the data; Szűcs D, Béres NJ, Sziksz E and Vannay A wrote the paper.
Supported by Hungarian Scientific Research Fund (OTKA), No. K105530, No. K108688, No. K116928, No. PD105361 and No. LP008/2016.
Institutional review board statement: The study was reviewed and approved by the Medical Research Council Scientific and Research Committee Institutional Review Board. This work was approved by TUKEB No. 10408/2012.
Conflict-of-interest statement: None of the authors have any conflict of interest or financial disclosures.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dániel Szűcs, MD, Department of Pediatrics and Pediatric Health Care Center, University of Szeged, Hungary, Korányi fasor 14-15., H-6725 Szeged, Hungary. firstname.lastname@example.org
Telephone: +36-62-545330 Fax: +36-62-545329
Received: March 25, 2016
Peer-review started: March 26, 2016
First decision: May 12, 2016
Revised: June 2, 2016
Accepted: June 15, 2016
Article in press: June 15, 2016
Published online: July 14, 2016