Retrospective Cohort Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 28, 2016; 22(20): 4891-4900
Published online May 28, 2016. doi: 10.3748/wjg.v22.i20.4891
Rectal cancer staging: Multidetector-row computed tomography diagnostic accuracy in assessment of mesorectal fascia invasion
Davide Ippolito, Silvia Girolama Drago, Cammillo Talei Franzesi, Davide Fior, Sandro Sironi
Davide Ippolito, Silvia Girolama Drago, Cammillo Talei Franzesi, Davide Fior, Sandro Sironi, School of Medicine, University of Milano-Bicocca, Milan, 20900 Monza (MB), Italy
Davide Ippolito, Silvia Girolama Drago, Cammillo Talei Franzesi, Davide Fior, Sandro Sironi, Department of Diagnostic Radiology, H. San Gerardo Hospital, Milan, 20900 Monza (MB), Italy
Author contributions: Ippolito D was guarantor of integrity of entire study and conception the study; Ippolito D and Drago SG contributed to study design, acquisition, data analysis/interpretation and statistical analysis; Ippolito D, Drago SG and Franzesi CT contributed to study design, and clinical studies; Franzesi CT and Fior D contributed to literature research; Drago SG contributed to manuscript preparation; Ippolito D and Sironi S contributed to manuscript definition of intellectual content; Ippolito D and Franzesi CT contributed to manuscript editing; all authors contributed to manuscript revision/review; Ippolito D made manuscript final version approval.
Institutional review board statement: The study was reviewed and approved by the H. San Gerardo Institutional Review Board.
Informed consent statement: Every patient gave his informed consent, as required by our Institution.
Conflict-of-interest statement: All the authors are aware of the content of the manuscript and have no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Davide Ippolito, MD, Department of Diagnostic Radiology, H. San Gerardo Hospital, Via Pergolesi 33, Milan, 20900 Monza (MB), Italy.
Telephone: +39-02-64488265 Fax: +39-02-64488299
Received: January 28, 2016
Peer-review started: January 30, 2016
First decision: March 7, 2016
Revised: March 24, 2016
Accepted: April 7, 2016
Article in press: April 7, 2016
Published online: May 28, 2016
Core Tip

Core tip: The introduction of new generation of multidetector-row computed tomography (MDCT) scanner allowed thin-collimation scanning and high spatial resolution, resulting in improved multiplanar reconstructions (MPRs) and could be potentially useful, in a single examination, for local staging and distant metastases evaluation in rectal cancer patients. On these basis in our study we assessed the accuracy of high row number MDCT for the prediction of tumor invasion of the mesorectal fascia, being MRI findings as reference standard, and whether the addition of high-resolution MPR images can provide greater accuracy.