Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells
Ling Zeng, Hai-Yun Zhou, Na-Na Tang, Wei-Feng Zhang, Gui-Jun He, Bo Hao, Ya-Dong Feng, Hong Zhu, Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China
Author contributions: Zhu H designed the research; Tang NN, Zhang WF and He GJ performed the research; Hao B, Feng YD and Zhu H analyzed the data; Zeng L and Zhou HY wrote the paper.
Supported by the National Natural Science Foundation of China, No. 30800511.
Institutional review board statement: The study was reviewed and approved by The First Affiliated Hospital of Nanjing Medical University Institutional Review Board.
Conflict-of-interest statement: To the best of our knowledge, no conflict of interest exists.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at firstname.lastname@example.org. Participants gave informed consent for data sharing. No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hong Zhu, MD, PhD, Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guang Zhou Road, Gulou District, Nanjing 210029, Jiangsu Province, China. email@example.com
Telephone: +86-25-86862684 Fax: +86-25-86862684
Received: October 10, 2015
Peer-review started: October 12, 2015
First decision: March 7, 2016
Revised: March 20, 2016
Accepted: April 15, 2016
Article in press: April 15, 2016
Published online: May 28, 2016