Published online Oct 14, 2015. doi: 10.3748/wjg.v21.i38.10790
Peer-review started: March 28, 2015
First decision: April 24, 2015
Revised: May 20, 2015
Accepted: August 31, 2015
Article in press: August 31, 2015
Published online: October 14, 2015
Core tip: The distribution patterns of hepatitis C virus (HCV) infection are related to different status of public health and the presence of risk factors in the society. In Iran, the predominance of risk factors for transmission of HCV has changed from blood transfusion to intravenous drug use; and due to the growth in the number of injecting drug users, the prevalence of HCV infection is rising in the country. Even the recent changes in the distribution pattern of HCV genotypes confirm this issue. Overall, the epidemiology of HCV is changing in Iran. Therefore, this review was conducted to present a clear view about current epidemiology of HCV in Iran.