Meta-Analysis
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 28, 2015; 21(24): 7577-7583
Published online Jun 28, 2015. doi: 10.3748/wjg.v21.i24.7577
Updated meta-analysis of pancreatic stent placement in preventing post-endoscopic retrograde cholangiopancreatography pancreatitis
Jin-He Fan, Jun-Bo Qian, Ya-Min Wang, Rui-Hua Shi, Cheng-Jin Zhao
Jin-He Fan, Jun-Bo Qian, Ya-Min Wang, Cheng-Jin Zhao, Department of Gastroenterology, Nantong First People’s Hospital, Nantong 226001, Jiangsu Province, China
Rui-Hua Shi, Department of Gastroenterology, People’s Hospital of Jiangsu Province, Nanjing 210029, Jiangsu Province, China
Author contributions: Fan JH carried out the studies, participated in collecting data, and drafted the manuscript; Qian JB performed the statistical analysis and participated in study design; Wang YM, Shi RH and Zhao CJ helped to draft the manuscript; all authors read and approved the final manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jun-Bo Qian, MD, Department of Gastroenterology, Nantong First People’s Hospital, No. 6 North Haier Gang, Nantong 226001, Jiangsu Province, China. medscifjh@126.com
Telephone: +86-21-85061285 Fax: +86-21-64085875
Received: May 29, 2014
Peer-review started: May 30, 2014
First decision: June 18, 2014
Revised: September 19, 2014
Accepted: January 21, 2015
Article in press: January 22, 2015
Published online: June 28, 2015
Core Tip

Core tip: Pancreatitis is one of the most common and severe complications after endoscopic retrograde cholangiopancreatography (ERCP). The reported incidence of post-ERCP pancreatitis (PEP) varies between 2% and 7% in prospective trials and may be as high as 30%-50% in high-risk patients. Although a previous meta-analysis has indicated that pancreatic duct stent placement can prevent PEP, particularly in high-risk patients, there is a lack of high-quality evidence-based studies based on appropriate numbers of well-validated publications. Therefore, an updated meta-analysis was conducted to investigate stents in preventing PEP.